BDBM50106469 CHEMBL269029::FGGFTCARKCARK::cyclo[Cys6,Cys10]N/OFQ(1-13)NH2

SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=YCXQOGDEHMJXPM-UHFFFAOYSA-N

Data  1 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106469   

TargetNociceptin receptor(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106469(FGGFTCARKCARK | cyclo[Cys6,Cys10]N/OFQ(1-13)NH2 | ...)
Affinity DataIC50: 0.833nMAssay Description:Displacement of [3H]NC from human ORL1 receptor expressing HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106469(FGGFTCARKCARK | cyclo[Cys6,Cys10]N/OFQ(1-13)NH2 | ...)
Affinity DataEC50:  31.3nMAssay Description:Efficacy for human ORL1 receptor expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106469(FGGFTCARKCARK | cyclo[Cys6,Cys10]N/OFQ(1-13)NH2 | ...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106469(FGGFTCARKCARK | cyclo[Cys6,Cys10]N/OFQ(1-13)NH2 | ...)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed