BDBM50105884 9-(3-Guanidino-propyl)-6-(1H-indol-3-ylmethyl)-12-naphthalen-2-ylmethyl-5,8,11,14,17-pentaoxo-1,4,7,10,13pentaaza-cycloheptadecane-3-carboxylic acid::CHEMBL331728

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)CCC(=O)NCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O

InChI Key InChIKey=OXIJPFTXSOSKGQ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105884   

TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105884(9-(3-Guanidino-propyl)-6-(1H-indol-3-ylmethyl)-12-...)
Affinity DataEC50: >5.00E+3nMAssay Description:Increase in intracellular cAMP in CHO cells expressing human melanocortin receptor 5.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105884(9-(3-Guanidino-propyl)-6-(1H-indol-3-ylmethyl)-12-...)
Affinity DataKi:  110nMAssay Description:Binding affinity against human melanocortin receptor 4 (hMC4R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105884(9-(3-Guanidino-propyl)-6-(1H-indol-3-ylmethyl)-12-...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity against human melanocortin receptor 3 (hMC3R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105884(9-(3-Guanidino-propyl)-6-(1H-indol-3-ylmethyl)-12-...)
Affinity DataKi:  4.80E+3nMAssay Description:Binding affinity against human melanocortin receptor 5 (hMC5R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed