BDBM50105799 CHEMBL3597548

SMILES CN(Cc1ccccc1)Cc1ccc(\C=C2/Cc3ccc(OCCCCCN4CCC(CC4)c4ccccc4)cc3C2=O)cc1

InChI Key InChIKey=LFWRLICXQATICR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50105799   

TargetBeta-secretase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50105799(CHEMBL3597548)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated with enzyme for 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50105799(CHEMBL3597548)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed