BDBM50105771 6-(4-chlorophenyl)-13-methoxy-19-(2-methylallyl)-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-2-ol::CHEMBL318957::Naltrindole analogue

SMILES COc1ccc2CC3N(CC(C)=C)CCC45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-c1ccc(Cl)cc1

InChI Key InChIKey=SVFVXLQUTFNIGW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105771   

TargetDelta-type opioid receptor(Rat)
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)

Curated by ChEMBL
LigandPNGBDBM50105771(Naltrindole analogue | 6-(4-chlorophenyl)-13-metho...)
Affinity DataKi:  257nMAssay Description:Binding affinity against Opioid receptor delta 1 from rat brain membranes using [3H]DADLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105771(Naltrindole analogue | 6-(4-chlorophenyl)-13-metho...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105771(Naltrindole analogue | 6-(4-chlorophenyl)-13-metho...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)

Curated by ChEMBL
LigandPNGBDBM50105771(Naltrindole analogue | 6-(4-chlorophenyl)-13-metho...)
Affinity DataKi:  3.24E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 from guinea pig brain membranes using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105771(Naltrindole analogue | 6-(4-chlorophenyl)-13-metho...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed