BDBM50105191 4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL419046

SMILES NC(=O)c1cc2c(Oc3ccc(\C=C\C(=O)N4CCOCC4)cc3)cncc2s1

InChI Key InChIKey=YMFWNFLVGCSPLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105191   

TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105191(4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-th...)
Affinity DataIC50: 25nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105191(4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-th...)
Affinity DataIC50: 16nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105191(4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-th...)
Affinity DataIC50: 140nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed