BDBM50104854 CHEMBL114393::N-[2-(2,3-Dihydro-benzofuran-4-yl)-cyclopropanecarbonyl]-guanidine

SMILES NC(=N)NC(=O)[C@H]1C[C@@H]1c1cccc2OCCc12

InChI Key InChIKey=PIZBQEGYQOWNTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104854   

TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104854(N-[2-(2,3-Dihydro-benzofuran-4-yl)-cyclopropanecar...)
Affinity DataIC50: 120nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104854(N-[2-(2,3-Dihydro-benzofuran-4-yl)-cyclopropanecar...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human NHE1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed