BDBM50104297 CHEMBL3594130::US20240190828, Compound 19

SMILES Cc1ccccc1C1NC(=O)c2ccccc2N1

InChI Key InChIKey=HEXRIGFWUUMZHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50104297   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104297(CHEMBL3594130 | US20240190828, Compound 19)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50104297(CHEMBL3594130 | US20240190828, Compound 19)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50104297(CHEMBL3594130 | US20240190828, Compound 19)
Affinity DataIC50: 4.96E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent