BDBM50103899 CHEMBL3594105

SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=UFYWONKSWCXKNY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50103899   

TargetMacrophage-stimulating protein receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50103899(CHEMBL3594105)
Affinity DataIC50: 270nMAssay Description:Inhibition of Ron (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50103899(CHEMBL3594105)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50103899(CHEMBL3594105)
Affinity DataIC50: 93nMAssay Description:Inhibition of VEGFR-2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50103899(CHEMBL3594105)
Affinity DataIC50: 38nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50103899(CHEMBL3594105)
Affinity DataIC50: 134nMAssay Description:Inhibition of FLT-3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50103899(CHEMBL3594105)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed