BDBM50102785 2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL330244

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc(Br)c1O

InChI Key InChIKey=WTZSIVZMLBYQIH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102785   

TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102785(2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  250nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102785(2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  300nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102785(2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102785(2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102785(2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102785(2-(3-Bromo-2-hydroxy-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed