BDBM50101429 2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetamide::2-(1H-indol-3-yl)-N-(4-nitrobenzyl)-2-oxoacetamide::CHEMBL74302

SMILES [O-][N+](=O)c1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1

InChI Key InChIKey=SQVFGSDZEHNBTN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101429   

LigandPNGBDBM50101429(2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]flumazenil binding to rat alpha-1-beta-2-gamma-2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50101429(2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50101429(2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...)
Affinity DataKi:  58nMAssay Description:Inhibition of [3H]flumazenil binding to rat alpha-5-beta-3-gamma-2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50101429(2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50101429(2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-2-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50101429(2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of [3H]flumazenil binding to rat alpha-3-beta-2-gamma-2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed