BDBM50100711 CHEMBL56677::[5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-dimethyl-amine

SMILES CN(C)c1ccc(cn1)C1CC2CCC1N2

InChI Key InChIKey=MKOQIVDOPMBHHG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100711   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100711([5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-d...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100711([5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-d...)
Affinity DataKi:  26.4nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100711([5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-d...)
Affinity DataKi: >100nMAssay Description:Binding affinity towards rat alpha2-beta2 neuronal nAChR expressed in Xenopus oocytes using [3H]epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100711([5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-d...)
Affinity DataKi: >100nMAssay Description:Binding affinity towards rat Nicotinic acetylcholine receptor alpha4-beta2 expressed in Xenopus oocytes using [3H]epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100711([5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-yl]-d...)
Affinity DataKi: >100nMAssay Description:Binding affinity towards rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus oocytes using [3H]epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed