BDBM50100470 CHEMBL303595::N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-1-ylmethyl)-amino]-9H-purin-3-ylmethyl}-tetrahydro-furan-3-yl)-3,4-dimethoxy-benzamide

SMILES COc1ccc(cc1OC)C(=O)N[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NCc3cccc4ccccc34)ncnc12

InChI Key InChIKey=VYHODKZCPLXEDM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100470   

TargetGlyceraldehyde-3-phosphate dehydrogenase, cytosolic(Leishmania mexicana)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100470(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-1-y...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against Leishmania mexicana GAPDHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100470(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-1-y...)
Affinity DataIC50: 4.70E+4nMAssay Description:In vitro inhibition of Trypanosoma brucei GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100470(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-1-y...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibition of Trypanosoma cruzi GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100470(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-1-y...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of rabbit muscle GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed