BDBM50099406 CHEMBL3344272

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)Cc1ccccc1)C(C)C)[C@@H](O)CC(=O)NCCc1ccccc1

InChI Key InChIKey=PQZHZCPKSLRZNY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099406   

TargetPlasmepsin V(Plasmodium falciparum (isolate 3D7))
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50099406(CHEMBL3344272)
Affinity DataIC50: 19nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50099406(CHEMBL3344272)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50099406(CHEMBL3344272)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetPlasmepsin V(malaria parasite P. vivax)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50099406(CHEMBL3344272)
Affinity DataIC50: 24nMAssay Description:Inhibition of Plasmodium vivax plasmepsin V by fluorogenic PEXEL cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed