BDBM50098921 (R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL415482

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(Cc2ccccc2)C(=O)C[C@@H]1C(=O)NO

InChI Key InChIKey=GETQXLAMYOMSJS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098921   

TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098921((R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098921((R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098921((R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098921((R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[...)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098921((R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[...)
Affinity DataIC50: 88nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098921((R)-1-Benzyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed