BDBM50098903 CHEMBL3330060

SMILES N[C@@H](CC(=O)N1C[C@@H](F)C[C@H]1C#N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=ROKKOEGCWJIYBM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50098903   

TargetDipeptidyl peptidase 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 5.06E+4nMAssay Description:Inhibition of DPP7 (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant DPP4 expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 330nMAssay Description:Inhibition of DPP9 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of FAP (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of DPP8 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells after 20 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 9.77E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells after 20 mins by thallium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50098903(CHEMBL3330060)
Affinity DataIC50: 5.65E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed