BDBM50098673 17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinan

SMILES CC(=C)N1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O

InChI Key InChIKey=AQESDYHCPQZRRJ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098673   

TargetDelta-type opioid receptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098673(17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epox...)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity of compound on agonist stimulated [35S]GTP-gamma-S binding on delta-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098673(17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epox...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]DADLE at delta-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098673(17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epox...)
Affinity DataKi:  200nMAssay Description:Antagonist activity of compound on agonist stimulated [35S]GTP-gamma-S binding on mu-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098673(17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epox...)
Affinity DataKi:  740nMAssay Description:Antagonist activity of compound on U50,488H stimulated [35S]GTP-gamma-S binding to opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098673(17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epox...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]U-69593 at opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098673(17-(2-methyl-2-propenyl)-6,7-dehydro-4,5alpha-epox...)
Affinity DataKi:  7.90E+3nMAssay Description:Displacement of [3H]DAMGO at mu-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed