BDBM50097967 3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenol::3-{4-Amino-7-[1-(2-hydroxy-ethyl)-piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-phenol::CHEMBL169780

SMILES Nc1ncnc2n(cc(-c3cccc(O)c3)c12)C1CCN(CCO)CC1

InChI Key InChIKey=WJSCDYSIDGEWEB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50097967   

TargetEpidermal growth factor receptor(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of autophosphorylation of epidermal growth factor receptor (EGF-R) in a cellular assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 600nMAssay Description:Concentration required for inhibition of c-Src mediated phosphorylation of Fak in IC8.1 fibroblast cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 360nMAssay Description:Tested for inhibitory activity against Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)
Affinity DataIC50: 98nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed