BDBM50097955 7-Cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL352954

SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)C1CCCC1

InChI Key InChIKey=SFSJABJVSLHBAD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097955   

TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097955(7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097955(7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Epidermal growth factor receptor (EGF-R) tyrosine kinase activity More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50097955(7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 126nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097955(7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097955(7-cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed