BDBM50097954 7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::7-cyclopentyl-5-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL170724

SMILES COc1ccc(cc1)-c1cn(C2CCCC2)c2ncnc(N)c12

InChI Key InChIKey=BRUSFAZPHIPJRR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097954   

TargetEpidermal growth factor receptor(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Epidermal growth factor receptor (EGF-R) tyrosine kinase activity More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed