BDBM50097947 CHEMBL352801::{3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutyl}-methanol

SMILES COc1cccc(c1)-c1cn(C2CC(CO)C2)c2ncnc(N)c12

InChI Key InChIKey=CAHQAXRCSXNZRF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097947   

TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097947({3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097947({3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 420nMAssay Description:Inhibition of Epidermal growth factor receptor (EGF-R) tyrosine kinase activity More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097947({3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097947({3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed