BDBM50097694 CHEMBL3590190

SMILES CC(C)N(CCNC(=O)c1ccc2CN(CCc2c1)S(=O)(=O)c1c(C)cc(C)cc1C)Cc1ccccc1

InChI Key InChIKey=QLOPMFWLQWNBML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097694   

TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50: 113nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50: 1.12E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50: 930nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed