BDBM50097266 (R)-N*1*-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methoxy-biphenyl-4-yl)-propyl]-succinamide::CHEMBL345306

SMILES COc1cc(CCC[C@H](CC(=O)NO)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)ccc1-c1ccccc1

InChI Key InChIKey=PCGCWQHPTVXXQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097266   

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097266((R)-N*1*-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylca...)
Affinity DataIC50: 110nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-3 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097266((R)-N*1*-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylca...)
Affinity DataIC50: 1.70E+3nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-2 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097266((R)-N*1*-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylca...)
Affinity DataIC50: 110nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed