BDBM50097102 2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-carboxylic acid furan-2-ylmethyl ester::CHEMBL150266

SMILES Cc1cc(Cl)cc2c(cc(nc12)-c1ccc(Br)cc1)C(=O)OCc1ccco1

InChI Key InChIKey=FFOCYOZUAILUNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097102   

TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097102(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 70nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097102(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to prolineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed