BDBM50096071 5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-pentanoic acid::CHEMBL134615

SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCC(O)=O

InChI Key InChIKey=MWSSXNGFNPPBDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096071   

TargetTrypanothione reductase(Trypanosoma cruzi)
Umr 8525 Cnrs - Université

Curated by ChEMBL
LigandPNGBDBM50096071(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 uM T(S)2.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Umr 8525 Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50096071(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Plasmodium falciparum Glutathione ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Umr 8525 Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50096071(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro inhibition of human Glutathione ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed