BDBM50095450 2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol::CHEMBL330673

SMILES NCCCCCC(CCN)SC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=YETXSQDQSWLLJR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50095450   

TargetSpermidine synthase(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSpermidine synthase(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSpermidine synthase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSpermine synthase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against spermine synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSpermidine synthase(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against spermidine synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed