BDBM50095434 CHEMBL3589912

SMILES CN(CCN)Cc1cn[nH]c1-c1ccc(F)cc1

InChI Key InChIKey=WJJPSVIYQWOSFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095434   

LigandPNGBDBM50095434(CHEMBL3589912)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095434(CHEMBL3589912)
Affinity DataIC50: 67nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT8 expressed in Escherichia coli (BL21(DE3) pre-incubated for 30 mins before addition of a [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095434(CHEMBL3589912)
Affinity DataIC50: 11nMAssay Description:Inhibition of FLAG and hexa-histidine tagged full-length human PRMT6 expressed in HEK293F cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed