BDBM50095319 2-Methoxy-5-(3,4,5-trimethoxy-phenylamino)-phenol::CHEMBL150463

SMILES COc1ccc(Nc2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=MJYKDEBIQGCYQN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095319   

TargetTubulin beta-1 chain(Human)
University of Salford

Curated by ChEMBL
LigandPNGBDBM50095319(2-Methoxy-5-(3,4,5-trimethoxy-phenylamino)-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin alpha-1A/beta chain(Pig)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50095319(2-Methoxy-5-(3,4,5-trimethoxy-phenylamino)-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2018
Entry Details Article
PubMed
TargetTubulin alpha-1A/beta chain(Pig)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50095319(2-Methoxy-5-(3,4,5-trimethoxy-phenylamino)-phenol ...)
Affinity DataIC50: 2.98E+5nMAssay Description:Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2018
Entry Details Article
PubMed