BDBM50095312 CHEMBL2324355

SMILES Cc1nocc1C(=O)Nc1ccc(c(N)n1)-c1ccccc1OC(F)(F)F

InChI Key InChIKey=LJBDZHNZGFGQNL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50095312   

LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 260nMAssay Description:Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.2 expressed in SHSY5Y cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.3 expressed in SHSY5Y cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.7 expressed in SHSY5Y cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50: 530nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed