BDBM50095310 CHEMBL3589894

SMILES CNC(=O)c1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl

InChI Key InChIKey=HPIUHDCRVYDAEJ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50095310   

LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Nav1.2 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Nav1.3 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Nav1.7 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 190nMAssay Description:Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed