BDBM50093086 1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-methyl-oxime::CHEMBL309087

SMILES CO\N=C(/COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(CCN1CCC(O)(CC1)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ORMFBQJKAWHTKC-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50093086   

TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against human tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  21nMAssay Description:Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]NKA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against human tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  25nMAssay Description:Binding affinity against recombinant human tachykinin receptor 1 in CHO cells using [3H]-Sar SP as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed