BDBM50092227 7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL69638

SMILES Nc1ncnc2n(cc(-c3cccc(Oc4ccccc4)c3)c12)C1CCCC1

InChI Key InChIKey=OWDYYQABYMVBBC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50092227   

TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092227(7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed