BDBM50092074 CHEMBL3582417::US9296728, 12

SMILES OC(=O)C(=C\c1ccc(cc1)N1CCCCC1)\C#N

InChI Key InChIKey=JADPBIFXTKFCDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092074   

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092074(CHEMBL3582417 | US9296728, 12)
Affinity DataIC50: 110nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2017
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092074(CHEMBL3582417 | US9296728, 12)
Affinity DataIC50: 140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed