BDBM50092069 CHEMBL3582422::US9296728, 20
SMILES COc1cc(ccc1\C=C(/C#N)C(O)=O)N(c1ccccc1)c1ccccc1
InChI Key InChIKey=OOKBWQIMMUTDEE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50092069
Affinity DataIC50: 8nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management
Curated by ChEMBL
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management
Curated by ChEMBL
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair