BDBM50091737 (S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-ethoxy)-benzoylamino]-propionic acid::2-((S)-Benzenesulfonylamino)-3-[4-(2-piperidin-4-yl-ethoxy)-benzoylamino]-propionic acid::2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-ethoxy)-benzoylamino]-propionic acid::CHEMBL59562

SMILES OC(=O)[C@H](CNC(=O)c1ccc(OCCC2CCNCC2)cc1)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=UIJBJQDAZCEJGM-UHFFFAOYSA-N

Data  8 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50091737   

TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Vitronectin receptor, integrin alphaV-beta3 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 10nMAssay Description:Inhibition of integrin alphaIIb-beta3 in platelet aggregation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 0.810nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataKd:  0.160nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 13nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]nonpeptide ligand (compound 7) from purified human recombinant alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]echistatin from human recombinant alpha-v beta-3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed