BDBM50091626 5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL326742

SMILES OC1(Cc2ccccc2)CCN(CC#Cc2ccc3[nH]c(=O)[nH]c3c2)CC1

InChI Key InChIKey=ALAHLCCSSRTDAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091626   

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091626(5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-yn...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091626(5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-yn...)
Affinity DataIC50: 8.60E+4nMAssay Description:Displacement of [3H]raclopride at Dopamine receptor D2 in brain striata (n=1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091626(5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-yn...)
Affinity DataIC50: 19nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091626(5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-yn...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed