BDBM50091625 5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indole::CHEMBL114514

SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1ccc2[nH]ccc2c1

InChI Key InChIKey=ILABISIOLQXNHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091625   

TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091625(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091625(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091625(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indo...)
Affinity DataIC50: 630nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed