BDBM50090972 3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester::CHEMBL89469

SMILES COC(=O)C1=C(CC2CCC1N2C)c1ccc(F)cc1

InChI Key InChIKey=ZECSPXOBAAGUES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090972   

TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50090972(3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 7.99E+3nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50090972(3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 408nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50090972(3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 408nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50090972(3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 7.99E+3nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed