BDBM50090679 2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid::CHEMBL77981::[2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid

SMILES OC(=O)Cc1ccccc1Nc1cc(Cl)ccc1Cl

InChI Key InChIKey=JSJQNYIFLKCXRE-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090679   

TargetInterleukin-8(Human)
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50090679([2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50090679([2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid ...)
Affinity DataIC50: 1.00E+7nMAssay Description:In vitro inhibition of bovine prostaglandin G/H synthase, using bovine seminal vesicle microsomal preparations; IC50 in umol/LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50090679([2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid ...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of COX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article

TargetCytochrome P450 2C9(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50090679([2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity measured on human cytochrome P450 2C9 (CYP2C9) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed