BDBM50090259 (4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-phosphinic acid::2-(((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)carbamoyl)-4-phenylbutyl(4-benzylbenzyl)phosphinic acid::CHEMBL290377

SMILES CNC(=O)[C@@H](NC(=O)C(CCc1ccccc1)CP(O)(=O)Cc1ccc(Cc2ccccc2)cc1)C(C)(C)C

InChI Key InChIKey=UTSFQPTVPZNJJH-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50090259   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 692nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed