BDBM50089779 4-cyclopropylmethyl-14-(3,4-diformylphenylcarboxamidomethylcarboxamido)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene

SMILES Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CC[C@@]35O)NC(=O)CNC(=O)c1ccc(C=O)c(C=O)c1

InChI Key InChIKey=IROYYIATGDSDTC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089779   

TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089779(4-cyclopropylmethyl-14-(3,4-diformylphenylcarboxam...)
Affinity DataKi:  0.450nMAssay Description:Inhibition of [3H]- diprenorphine binding to Opioid receptor mu 1 (83 fmol/mg protein) stably expressed in membranes from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089779(4-cyclopropylmethyl-14-(3,4-diformylphenylcarboxam...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of [3H]diprenorphine binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50089779(4-cyclopropylmethyl-14-(3,4-diformylphenylcarboxam...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [3H]- diprenorphine binding to Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed