BDBM50088700 1-{4-Hydroxy-5-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-2-oxo-pentyl}-piperidin-2-one::CHEMBL11828

SMILES CC(C)Oc1ccccc1N1CCN(CC(O)CC(=O)CN2CCCCC2=O)CC1

InChI Key InChIKey=UTACGRWSJNDCLR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088700   

TargetAlpha-1A adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088700(1-{4-Hydroxy-5-[4-(2-isopropoxy-phenyl)-piperazin-...)
Affinity DataKi:  28nMAssay Description:Binding affinity for human Alpha-1A adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088700(1-{4-Hydroxy-5-[4-(2-isopropoxy-phenyl)-piperazin-...)
Affinity DataKi:  253nMAssay Description:Binding affinity for human Alpha-1D adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088700(1-{4-Hydroxy-5-[4-(2-isopropoxy-phenyl)-piperazin-...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity for human Alpha-1B adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed