BDBM50088520 CHEMBL3526575

SMILES COc1ccc(cc1OC)S(=O)(=O)Nc1nc(c(CN2CCCCC2)s1)-c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=AOZLMMDVJOGGEQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50088520   

TargetKynurenine 3-monooxygenase(Mouse)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Wistar rat KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetKynurenine 3-monooxygenase(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed