BDBM50088167 CHEMBL3427246

SMILES Cc1noc(C)c1[C@@H]1C[C@H](N=C(N)S1)c1cccc(c1)-c1cncnc1

InChI Key InChIKey=OTJAZSWMNQGVHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088167   

TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088167(CHEMBL3427246)
Affinity DataIC50: 230nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088167(CHEMBL3427246)
Affinity DataIC50: 230nMAssay Description:Inhibition of BACE1 in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta 40 or amyloid beta 42 production incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed