BDBM50087841 CHEMBL3426804

SMILES ONC(=O)\C=C\c1ccc(NC(=O)C(Cc2ccccc2)c2ccccc2)cn1

InChI Key InChIKey=UQSIPNLHOWORHA-UHFFFAOYSA-N

Data  27 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50087841   

TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of human recombinant HDAC5 using fluorogenic class IIa (Bos-Lys(trifluoroacetyl)-AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 612nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic diacetylated p53 (379-382 residues) (RHKK(Ac)K(Ac)AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic class IIa (Bos-Lys(trifluoroacetyl)-AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant HDAC11 using fluorogenic class IIa (Bos-Lys(trifluoroacetyl)-AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant HDAC10 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human recombinant HDAC9 using fluorogenic class IIa (Bos-Lys(trifluoroacetyl)-AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of human recombinant HDAC7 using fluorogenic class IIa (Bos-Lys(trifluoroacetyl)-AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 610nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of recombinant HDAC11 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed