BDBM50087518 (R)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol::6-fluoronorepinehprine::CHEMBL295072

SMILES NC[C@H](O)c1ccc(O)c(O)c1F

InChI Key InChIKey=FOTRTWXNJQSQJS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087518   

TargetBeta-2 adrenergic receptor(Dog)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50087518(6-fluoronorepinehprine | (R)4-(2-Amino-1-hydroxy-e...)
Affinity DataKi:  67nMAssay Description:Binding of [3H]dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50087518(6-fluoronorepinehprine | (R)4-(2-Amino-1-hydroxy-e...)
Affinity DataKi:  130nMAssay Description:Binding of [3H]dihydroalprenolol to beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50087518(6-fluoronorepinehprine | (R)4-(2-Amino-1-hydroxy-e...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]prazosin from human adrenergic Alpha-1B receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50087518(6-fluoronorepinehprine | (R)4-(2-Amino-1-hydroxy-e...)
Affinity DataKi:  1.16E+6nMAssay Description:Displacement of [3H]prazosin from human adrenergic beta2 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed