BDBM50087427 (E)-8-hydroxy-2-(3-hydroxy-4-methoxystyryl)quinoline-7-carboxylic acid::8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]-quinoline-7-carboxylic acid::8-hydroxy-2-(3-hydroxy-4-methoxystyryl)quinoline-7-carboxylic acid::CHEMBL37139

SMILES COc1ccc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc1O

InChI Key InChIKey=FSLDLBJGAMZARH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50087427   

TargetIntegrase(Human immunodeficiency virus type 1)
Université

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Université

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer (integration)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5/P25More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3alpha/betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse DYRK1A expressed in Escherichia coli after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50087427(8-Hydroxy-2-[2-(3-hydroxy-4-methoxy-phenyl)-vinyl]...)
Affinity DataIC50: 891nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed