BDBM50085354 CHEMBL60160::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-trifluoromethyl-phenyl)-propionamide

SMILES FC(F)(F)c1ccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)cc1

InChI Key InChIKey=HXSFNHKRHGFCAR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085354   

TargetChymotrypsin-like elastase family member 2A(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085354(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-triflu...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085354(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-triflu...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085354(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymase(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085354(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-triflu...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085354(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-triflu...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed