BDBM50085338 CHEMBL291397::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-m-tolyl-propionamide

SMILES Cc1cccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)c1

InChI Key InChIKey=BJEVPNLKGSXRCN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085338   

TargetTrypsin(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085338(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-m-tolyl-p...)
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085338(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-m-tolyl-p...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085338(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-m-tolyl-p...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085338(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-m-tolyl-p...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymase(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085338(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-m-tolyl-p...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed