BDBM50084979 3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)-2-hydroxymethyl-2,3-dihydro-benzo[1,4]dioxin-6-yl]-chromen-4-one::CHEMBL38464::Dehydrosilybin::Dehydrosilylbin

SMILES COc1cc(ccc1O)C1Oc2cc(ccc2OC1CO)-c1oc2cc(O)cc(=O)c2c(O)c1O

InChI Key InChIKey=LFTHENPBYWXXAI-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084979   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50084979(Dehydrosilylbin | 3,5,7-Trihydroxy-2-[3-(4-hydroxy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MRP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
University of Lyon 1

Curated by ChEMBL
LigandPNGBDBM50084979(Dehydrosilylbin | 3,5,7-Trihydroxy-2-[3-(4-hydroxy...)
Affinity DataKd:  2.20E+3nMAssay Description:Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-GlycoproteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Rat)
Pharmacy School of Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50084979(Dehydrosilylbin | 3,5,7-Trihydroxy-2-[3-(4-hydroxy...)
Affinity DataIC50: 8.03E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed