BDBM50084893 (S)-3-(dibenzo[b,d]furan-3-yl)-2-(phosphonomethylamino)propanoic acid::3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-propionic acid::CHEMBL146936

SMILES OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NCP(O)(O)=O

InChI Key InChIKey=CRUVAUSVWLATAE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084893   

TargetNeprilysin(Human)
Cea

Curated by ChEMBL
LigandPNGBDBM50084893(3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-prop...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Cea

Curated by ChEMBL
LigandPNGBDBM50084893(3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-prop...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human somatic ECE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084893(3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-prop...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibition of rat neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Cea

Curated by ChEMBL
LigandPNGBDBM50084893(3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-prop...)
Affinity DataIC50: 22nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed